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Professor Øyvind S. Bruland
 

Professor Øyvind S. Bruland

 

PubMed registered articles

Øyvind S. Bruland

Since not all peer reviewed papers will appear on PubMed, please visit the sub directory "Chronologically"

Publications by Øyvind Sverre Bruland

140 publications found

Publications in press

  1. Berner K, Johannesen TB, Berner A, Haugland HK, Bjerkehagen B, Bøhler PJ, Bruland OS
    Time-trends on incidence and survival in a nationwide and unselected cohort of patients with skeletal osteosarcoma
    Acta Oncol, 1-9 (in press)
    PubMed 24957555
  2. Ohnstad HO, Bruland OS, Taksdal I, Bjerkehagen B, Nenadovic M, Sæter G, Jørgensen LH, Hall KS
    Response to preoperative chemotherapy in patients undergoing resection of pulmonary metastasis from soft tissue sarcoma - a predictor of outcome?
    Acta Oncol (in press)
    PubMed 24697744

Publications 2014

  1. Repetto-Llamazares A, Abbas N, Bruland OS, Dahle J, Larsen RH (2014)
    Advantage of Lutetium-177 versus Radioiodine Immunoconjugate in Targeted Radionuclide Therapy of B-cell Tumors
    Anticancer Res, 34 (7), 3263-9
    PubMed 24982330
  2. Revheim ME, Hole KH, Bruland OS, Reitan E, Bjerkehagen B, Julsrud L, Seierstad T (2014)
    Multimodal functional imaging for early response assessment in GIST patients treated with imatinib
    Acta Oncol, 53 (1), 143-8
    PubMed 23710697
  3. Sartor O, Coleman R, Nilsson S, Heinrich D, Helle SI, O'Sullivan JM, Fosså SD, Chodacki A, Wiechno P, Logue J, Widmark A, Johannessen DC, Hoskin P, James ND, Solberg A, Syndikus I, Vogelzang NJ, O'Bryan-Tear CG, Shan M, Bruland ØS, Parker C (2014)
    Effect of radium-223 dichloride on symptomatic skeletal events in patients with castration-resistant prostate cancer and bone metastases: results from a phase 3, double-blind, randomised trial
    Lancet Oncol, 15 (7), 738-46
    PubMed 24836273

Publications 2013

  1. Abbas N, Heyerdahl H, Bruland ØS, Brevik EM, Dahle J (2013)
    Comparing high LET 227Th- and low LET 177Lu-trastuzumab in mice with HER-2 positive SKBR-3 xenografts
    Curr Radiopharm, 6 (2), 78-86
    PubMed 23551110
  2. Bjerkehagen B, Småstuen MC, Hall KS, Skjeldal S, Bruland ØS, Smeland S, Johannesen TB, Fosså SD (2013)
    Incidence and mortality of second sarcomas - a population-based study
    Eur J Cancer, 49 (15), 3292-302
    PubMed 23787025
  3. Dahle J, Repetto-Llamazares AH, Mollatt CS, Melhus KB, Bruland OS, Kolstad A, Larsen RH (2013)
    Evaluating antigen targeting and anti-tumor activity of a new anti-CD37 radioimmunoconjugate against non-Hodgkin's lymphoma
    Anticancer Res, 33 (1), 85-95
    PubMed 23267131
  4. Fløisand Y, Beiske K, Tjønnfjord GE, Heldal D, Bjerkehagen B, Revheim ME, Heim S, Bruland OS, Hall KS, Tierens A, Delabie J (2013)
    Malignant phyllodes tumor and acute megakaryoblastic leukemia sharing a common clonal origin
    Case Rep Hematol, 2013, 934781
    PubMed 24455338
  5. Heyerdahl H, Abbas N, Sponheim K, Mollatt C, Bruland Ø, Dahle J (2013)
    Targeted alpha therapy with 227Th-trastuzumab of intraperitoneal ovarian cancer in nude mice
    Curr Radiopharm, 6 (2), 106-16
    PubMed 23551111
  6. Jebsen NL, Engellau J, Engström K, Bauer HC, Monge OR, Muren LP, Eide GE, Trovik CS, Bruland OS (2013)
    Patterns of local recurrence and dose fractionation of adjuvant radiation therapy in 462 patients with soft tissue sarcoma of extremity and trunk wall
    Int J Radiat Oncol Biol Phys, 86 (5), 949-55
    PubMed 23725998
  7. Lagunova Z, Porojnicu AC, Aksnes L, Holick MF, Iani V, Bruland OS, Moan J (2013)
    Effect of vitamin D supplementation and ultraviolet B exposure on serum 25-hydroxyvitamin D concentrations in healthy volunteers: a randomized, crossover clinical trial
    Br J Dermatol, 169 (2), 434-40
    PubMed 23551243
  8. Mikalsen LT, Dhakal HP, Bruland ØS, Naume B, Borgen E, Nesland JM, Olsen DR (2013)
    The clinical impact of mean vessel size and solidity in breast carcinoma patients
    PLoS One, 8 (10), e75954
    PubMed 24146798
  9. Nilsson S, Franzén L, Parker C, Tyrrell C, Blom R, Tennvall J, Lennernäs B, Petersson U, Johannessen DC, Sokal M, Pigott K, O'Bryan-Tear CG, Thuresson M, Bolstad B, Bruland ØS (2013)
    Two-year survival follow-up of the randomized, double-blind, placebo-controlled phase II study of radium-223 chloride in patients with castration-resistant prostate cancer and bone metastases
    Clin Genitourin Cancer, 11 (1), 20-6
    PubMed 23021204
  10. Parker C, Nilsson S, Heinrich D, Helle SI, O'Sullivan JM, Fosså SD, Chodacki A, Wiechno P, Logue J, Seke M, Widmark A, Johannessen DC, Hoskin P, Bottomley D, James ND, Solberg A, Syndikus I, Kliment J, Wedel S, Boehmer S, Dall'Oglio M, Franzén L, Coleman R, Vogelzang NJ, O'Bryan-Tear CG et al. (2013)
    Alpha emitter radium-223 and survival in metastatic prostate cancer
    N Engl J Med, 369 (3), 213-23
    PubMed 23863050
  11. Revheim ME, Kristian A, Malinen E, Bruland ØS, Berner JM, Holm R, Joensuu H, Seierstad T (2013)
    Intermittent and continuous imatinib in a human GIST xenograft model carrying KIT exon 17 resistance mutation D816H
    Acta Oncol, 52 (4), 776-82
    PubMed 23480638
  12. Rusten E, Rødal J, Bruland Ø, Malinen E (2013)
    Biologic targets identified from dynamic 18FDG-PET and implications for image-guided therapy
    Acta Oncol, 52 (7), 1378-83
    PubMed 23981046
  13. Rusten E, Rødal J, Revheim ME, Skretting A, Bruland OS, Malinen E (2013)
    Quantitative dynamic ¹?FDG-PET and tracer kinetic analysis of soft tissue sarcomas
    Acta Oncol, 52 (6), 1160-7
    PubMed 23198721
  14. Sartor O, Hoskin P, Bruland OS (2013)
    Targeted radio-nuclide therapy of skeletal metastases
    Cancer Treat Rev, 39 (1), 18-26
    PubMed 22534284

Publications 2012

  1. Abbas N, Bruland ØS, Brevik EM, Dahle J (2012)
    Preclinical evaluation of 227Th-labeled and 177Lu-labeled trastuzumab in mice with HER-2-positive ovarian cancer xenografts
    Nucl Med Commun, 33 (8), 838-47
    PubMed 22643311
  2. Micu E, Baturaite Z, Juzeniene A, Bruland ØS, Moan JE (2012)
    Superficial-spreading and nodular melanomas in Norway: a comparison by body site distribution and latitude gradients
    Melanoma Res, 22 (6), 460-5
    PubMed 23010822
  3. Namløs HM, Kresse SH, Müller CR, Henriksen J, Holdhus R, Sæter G, Bruland OS, Bjerkehagen B, Steen VM, Myklebost O (2012)
    Global gene expression profiling of human osteosarcomas reveals metastasis-associated chemokine pattern
    Sarcoma, 2012, 639038
    PubMed 22518090
  4. Nilsson S, Strang P, Aksnes AK, Franzèn L, Olivier P, Pecking A, Staffurth J, Vasanthan S, Andersson C, Bruland ØS (2012)
    A randomized, dose-response, multicenter phase II study of radium-223 chloride for the palliation of painful bone metastases in patients with castration-resistant prostate cancer
    Eur J Cancer, 48 (5), 678-86
    PubMed 22341993

Publications 2011

  1. Abbas N, Heyerdahl H, Bruland OS, Borrebæk J, Nesland J, Dahle J (2011)
    Experimental ?-particle radioimmunotherapy of breast cancer using 227Th-labeled p-benzyl-DOTA-trastuzumab
    EJNMMI Res, 1 (1), 18
    PubMed 22214432
  2. Anfinsen KP, Devesa SS, Bray F, Troisi R, Jonasdottir TJ, Bruland OS, Grotmol T (2011)
    Age-period-cohort analysis of primary bone cancer incidence rates in the United States (1976-2005)
    Cancer Epidemiol Biomarkers Prev, 20 (8), 1770-7
    PubMed 21724855
  3. Anfinsen KP, Grotmol T, Bruland OS, Jonasdottir TJ (2011)
    Breed-specific incidence rates of canine primary bone tumors--a population based survey of dogs in Norway
    Can J Vet Res, 75 (3), 209-15
    PubMed 22210997
  4. Dahle J, Abbas N, Bruland ØS, Larsen RH (2011)
    Toxicity and relative biological effectiveness of alpha emitting radioimmunoconjugates
    Curr Radiopharm, 4 (4), 321-8
    PubMed 22202154
  5. Jebsen NL, Bruland ØS, Eriksson M, Engellau J, Turesson I, Folin A, Trovik CS, Hall KS (2011)
    Five-year results from a Scandinavian sarcoma group study (SSG XIII) of adjuvant chemotherapy combined with accelerated radiotherapy in high-risk soft tissue sarcoma of extremities and trunk wall
    Int J Radiat Oncol Biol Phys, 81 (5), 1359-66
    PubMed 20933339
  6. Mikalsen LT, Dhakal HP, Bruland OS, Nesland JM, Olsen DR (2011)
    Quantification of angiogenesis in breast cancer by automated vessel identification in CD34 immunohistochemical sections
    Anticancer Res, 31 (12), 4053-60
    PubMed 22199261
  7. Revheim ME, Hole KH, Bruland OS, Haugland HK, Hall KS, Seierstad T (2011)
    DW MRI for evaluation of treatment response to imatinib in a rectal gastrointestinal stromal tumour
    Acta Oncol, 50 (1), 148-50
    PubMed 21110775
  8. Revheim ME, Røe K, Bruland ØS, Bach-Gansmo T, Skretting A, Seierstad T (2011)
    Monitoring the effect of targeted therapies in a gastrointestinal stromal tumor xenograft using a clinical PET/CT
    Mol Imaging Biol, 13 (6), 1234-40
    PubMed 21161686
  9. Sartor O, Bruland O (2011)
    Stromal targeted therapies in prostate and renal cancer: new concepts and knowledge
    Clin Genitourin Cancer, 9 (1), 1-2
    PubMed 21925102
  10. Sartor O, Goeckeler W, Bruland O (2011)
    Stromal targeted therapy in bone metastatic prostate cancer: promise delivered
    Asian J Androl, 13 (6), 783-4
    PubMed 21857688
  11. Smeland S, Bruland OS, Hjorth L, Brosjö O, Bjerkehagen B, Osterlundh G, Jakobson A, Hall KS, Monge OR, Björk O, Alvegaard TA (2011)
    Results of the Scandinavian Sarcoma Group XIV protocol for classical osteosarcoma: 63 patients with a minimum follow-up of 4 years
    Acta Orthop, 82 (2), 211-6
    PubMed 21434784
  12. Zaikova O, Fosså SD, Bruland OS, Giercksky KE, Sandstad B, Skjeldal S (2011)
    Radiotherapy or surgery for spine metastases?
    Acta Orthop, 82 (3), 365-71
    PubMed 21434789

Publications 2010

  1. Cicarma E, Juzeniene A, Porojnicu AC, Bruland ØS, Moan J (2010)
    Latitude gradient for melanoma incidence by anatomic site and gender in Norway 1966-2007
    J Photochem Photobiol B, 101 (2), 174-8
    PubMed 20430639
  2. Dale E, Hårsaker V, Kristoffersen DT, Bruland O, Olsen DR (2010)
    CT density in lung cancer patients after radiotherapy sensitized by metoclopramide. A subgroup analysis of a randomized trial
    Strahlenther Onkol, 186 (3), 163-8
    PubMed 20165821
  3. Lagunova Z, Porojnicu AC, Grant WB, Bruland Ø, Moan JE (2010)
    Obesity and increased risk of cancer: does decrease of serum 25-hydroxyvitamin D level with increasing body mass index explain some of the association?
    Mol Nutr Food Res, 54 (8), 1127-33
    PubMed 20512788
  4. Moan J, Lagunova Z, Bruland O, Juzeniene A (2010)
    Seasonal variations of cancer incidence and prognosis
    Dermatoendocrinol, 2 (2), 55-7
    PubMed 21547098

Publications 2009

  1. Berg A, Dahl AA, Bruland ØS, Bjøro T, Aanensen MS, Fosså SD (2009)
    Definitive radiotherapy with adjuvant long-term antiandrogen treatment for locally advanced prostate cancer: health-related quality of life and hormonal changes
    Prostate Cancer Prostatic Dis, 12 (3), 269-76
    PubMed 19290019
  2. Brandal P, Bjerkehagen B, Bruland OS, Skjeldal S, Bogsrud TV, Hall KS (2009)
    Synchronous and metachronous skeletal osteosarcomas: the Norwegian Radium Hospital experience
    Acta Oncol, 48 (8), 1165-72
    PubMed 19863225
  3. Bruland ØS, Bauer H, Alvegaard T, Smeland S (2009)
    Treatment of osteosarcoma. The Scandinavian Sarcoma Group experience
    Cancer Treat Res, 152, 309-18
    PubMed 20213398
  4. Bruland ØS, Høifødt H, Hall KS, Smeland S, Fodstad Ø (2009)
    Bone marrow micrometastases studied by an immunomagnetic isolation procedure in extremity localized non-metastatic osteosarcoma patients
    Cancer Treat Res, 152, 509-15
    PubMed 20213412
  5. Hall KS, Eriksson M, Bruland OS, Engellau J, Trovik CS (2009)
    Treatment of soft tissue sarcoma of the extremity and trunk wall The Scandinavian Sarcoma Group perspective
    Acta Orthop., 80, 52-59
  6. Norum OJ, Bruland ØS, Gorunova L, Berg K (2009)
    Photochemical internalization of bleomycin before external-beam radiotherapy improves locoregional control in a human sarcoma model
    Int J Radiat Oncol Biol Phys, 75 (3), 878-85
    PubMed 19665318
  7. Revheim ME, Seierstad T, Berner JM, Bruland OS, Røe K, Ohnstad HO, Bjerkehagen B, Bach-Gansmo T (2009)
    Establishment and characterization of a human gastrointestinal stromal tumour (GIST) xenograft in athymic nude mice
    Anticancer Res, 29 (11), 4331-6
    PubMed 20032375
  8. Sande TA, Ruenes R, Lund JA, Bruland OS, Hornslien K, Bremnes R, Kaasa S (2009)
    Long-term follow-up of cancer patients receiving radiotherapy for bone metastases: results from a randomised multicentre trial
    Radiother Oncol, 91 (2), 261-6
    PubMed 19307034
  9. Schwarz R, Bruland O, Cassoni A, Schomberg P, Bielack S (2009)
    The role of radiotherapy in oseosarcoma
    Cancer Treat Res, 152, 147-64
    PubMed 20213389
  10. Smeland S, Bruland OS, Hjorth L, Brosjo O, Bjerkehagen B, Osterlundh G, Jakobson A, Hall KS, Monge OR, Bjork O, Alvegaard TA (2009)
    Scandinavian experience in classical osteosarcoma Results of the SSG XIV protocol
    Acta Orthop., 80, 60-66
  11. Søvik S, Skogmo HK, Andersen EK, Bruland ØS, Olsen DR, Malinen E (2009)
    DCEMRI of spontaneous canine tumors during fractionated radiotherapy: a pharmacokinetic analysis
    Radiother Oncol, 93 (3), 618-24
    PubMed 19747746

Publications 2008

  1. Berg A, Bruland ØS, Fosså SD, Nesland JM, Berner A, Schirmer C, Lilleby W (2008)
    Disseminated tumor cells in bone marrow following definitive radiotherapy for intermediate or high-risk prostate cancer
    Prostate, 68 (15), 1607-14
    PubMed 18655095
  2. Dahle J, Bruland OS, Larsen RH (2008)
    Relative biologic effects of low-dose-rate alpha-emitting 227Th-rituximab and beta-emitting 90Y-tiuexetan-ibritumomab versus external beam X-radiation
    Int J Radiat Oncol Biol Phys, 72 (1), 186-92
    PubMed 18722269
  3. Erikson A, Tufto I, Bjønnum AB, Bruland ØS, Davies Cde L (2008)
    The impact of enzymatic degradation on the uptake of differently sized therapeutic molecules
    Anticancer Res, 28 (6A), 3557-66
    PubMed 19189635
  4. Jebsen NL, Trovik CS, Bauer HC, Rydholm A, Monge OR, Hall KS, Alvegård T, Bruland OS (2008)
    Radiotherapy to improve local control regardless of surgical margin and malignancy grade in extremity and trunk wall soft tissue sarcoma: a Scandinavian sarcoma group study
    Int J Radiat Oncol Biol Phys, 71 (4), 1196-203
    PubMed 18207661
  5. Porojnicu AC, Bruland OS, Aksnes L, Grant WB, Moan J (2008)
    Sun beds and cod liver oil as vitamin D sources
    J Photochem Photobiol B, 91 (2-3), 125-31
    PubMed 18417354
  6. Søvik A, Kippenes Skogmo H, Bruland ØS, Rune Olsen D, Malinen E (2008)
    DCEMRI monitoring of canine tumors during fractionated radiotherapy
    Acta Oncol, 47 (7), 1249-56
    PubMed 18618342
  7. Vågane R, Bruland ØS, Fosså SD, Olsen DR (2008)
    Radiological and functional assessment of radiation-induced pulmonary damage following breast irradiation
    Acta Oncol, 47 (2), 248-54
    PubMed 18210300

Publications 2007

  1. Aksnes LH, Bruland ØS (2007)
    Some musculo-skeletal sequelae in cancer survivors
    Acta Oncol, 46 (4), 490-6
    PubMed 17497316
  2. Berg A, Berner A, Lilleby W, Bruland ØS, Fosså SD, Nesland JM, Kvalheim G (2007)
    Impact of disseminated tumor cells in bone marrow at diagnosis in patients with nonmetastatic prostate cancer treated by definitive radiotherapy
    Int J Cancer, 120 (8), 1603-9
    PubMed 17230512
  3. Berg A, Lilleby W, Bruland OS, Fosså SD (2007)
    10-year survival and quality of life in patients with high-risk pN0 prostate cancer following definitive radiotherapy
    Int J Radiat Oncol Biol Phys, 69 (4), 1074-83
    PubMed 17703896
  4. Dahle J, Borrebaek J, Jonasdottir TJ, Hjelmerud AK, Melhus KB, Bruland ØS, Press OW, Larsen RH (2007)
    Targeted cancer therapy with a novel low-dose rate alpha-emitting radioimmunoconjugate
    Blood, 110 (6), 2049-56
    PubMed 17536011
  5. Larsen RH, Borrebaek J, Dahle J, Melhus KB, Krogh C, Valan MH, Bruland OS (2007)
    Preparation of TH227-labeled radioimmunoconjugates, assessment of serum stability and antigen binding ability
    Cancer Biother Radiopharm, 22 (3), 431-7
    PubMed 17651051
  6. Nilsson S, Franzén L, Parker C, Tyrrell C, Blom R, Tennvall J, Lennernäs B, Petersson U, Johannessen DC, Sokal M, Pigott K, Yachnin J, Garkavij M, Strang P, Harmenberg J, Bolstad B, Bruland OS (2007)
    Bone-targeted radium-223 in symptomatic, hormone-refractory prostate cancer: a randomised, multicentre, placebo-controlled phase II study
    Lancet Oncol, 8 (7), 587-94
    PubMed 17544845
  7. Olsen DR, Bruland OS, Frykholm G, Norderhaug IN (2007)
    Proton therapy - a systematic review of clinical effectiveness
    Radiother Oncol, 83 (2), 123-32
    PubMed 17499374
  8. Porojnicu AC, Robsahm TE, Dahlback A, Berg JP, Christiani D, Bruland OS, Moan J (2007)
    Seasonal and geographical variations in lung cancer prognosis in Norway. Does Vitamin D from the sun play a role?
    Lung Cancer, 55 (3), 263-70
    PubMed 17207891
  9. Søvik A, Malinen E, Bruland ØS, Bentzen SM, Olsen DR (2007)
    Optimization of tumour control probability in hypoxic tumours by radiation dose redistribution: a modelling study
    Phys Med Biol, 52 (2), 499-513
    PubMed 17202629
  10. Søvik A, Malinen E, Skogmo HK, Bentzen SM, Bruland OS, Olsen DR (2007)
    Radiotherapy adapted to spatial and temporal variability in tumor hypoxia
    Int J Radiat Oncol Biol Phys, 68 (5), 1496-504
    PubMed 17674980

Publications 2006

  1. Aksnes LH, Hall KS, Folleraas G, Stenwig AE, Bjerkehagen B, Taksdal I, Winderen M, Bruland OS, Saeter G (2006)
    Management of high-grade bone sarcomas over two decades: the Norwegian Radium Hospital experience
    Acta Oncol, 45 (1), 38-46
    PubMed 16464794
  2. Bruland ØS (2006)
    [Jumping after the Swedes]
    Tidsskr Nor Laegeforen, 126 (5), 637
    PubMed 16505887
  3. Bruland ØS, Nilsson S, Fisher DR, Larsen RH (2006)
    High-linear energy transfer irradiation targeted to skeletal metastases by the alpha-emitter 223Ra: adjuvant or alternative to conventional modalities?
    Clin Cancer Res, 12 (20 Pt 2), 6250s-6257s
    PubMed 17062709
  4. Dahle J, Borrebaek J, Melhus KB, Bruland OS, Salberg G, Olsen DR, Larsen RH (2006)
    Initial evaluation of (227)Th-p-benzyl-DOTA-rituximab for low-dose rate alpha-particle radioimmunotherapy
    Nucl Med Biol, 33 (2), 271-9
    PubMed 16546683
  5. Jonasdottir TJ, Fisher DR, Borrebaek J, Bruland OS, Larsen RH (2006)
    First in vivo evaluation of liposome-encapsulated 223Ra as a potential alpha-particle-emitting cancer therapeutic agent
    Anticancer Res, 26 (4B), 2841-8
    PubMed 16886603
  6. Kaasa S, Brenne E, Lund JA, Fayers P, Falkmer U, Holmberg M, Lagerlund M, Bruland O (2006)
    Prospective randomised multicenter trial on single fraction radiotherapy (8 Gy x 1) versus multiple fractions (3 Gy x 10) in the treatment of painful bone metastases
    Radiother Oncol, 79 (3), 278-84
    PubMed 16793154
  7. Larsen RH, Saxtorph H, Skydsgaard M, Borrebaek J, Jonasdottir TJ, Bruland OS, Klastrup S, Harling R, Ramdahl T (2006)
    Radiotoxicity of the alpha-emitting bone-seeker 223Ra injected intravenously into mice: histology, clinical chemistry and hematology
    In Vivo, 20 (3), 325-31
    PubMed 16724665
  8. Lipton A, Berenson JR, Body JJ, Boyce BF, Bruland OS, Carducci MA, Cleeland CS, Clohisy DR, Coleman RE, Cook RJ, Guise TA, Pearse RN, Powles TJ, Rogers MJ, Roodman GD, Smith MR, Suva LJ, Vessella RL, Weilbaecher KN, King L (2006)
    Advances in treating metastatic bone cancer: summary statement for the First Cambridge Conference
    Clin Cancer Res, 12 (20 Pt 2), 6209s-6212s
    PubMed 17062702
  9. Malinen E, Søvik A, Hristov D, Bruland ØS, Olsen DR (2006)
    Adapting radiotherapy to hypoxic tumours
    Phys Med Biol, 51 (19), 4903-21
    PubMed 16985278

Publications 2005

  1. Bruland OS, Høifødt H, Saeter G, Smeland S, Fodstad O (2005)
    Hematogenous micrometastases in osteosarcoma patients
    Clin Cancer Res, 11 (13), 4666-73
    PubMed 16000559
  2. Brustugun OT, Reed W, Poulsen JP, Bruland OS (2005)
    Primary osteosarcoma of the breast
    Acta Oncol, 44 (7), 767-70
    PubMed 16227171
  3. Dale E, Hellebust TP, Bruland ØS, Olsen DR (2005)
    Comparative analyses of the dynamic properties of the bladder wall studied by repetitive pelvic CT scans of patients and cryo-sections of cadavers
    Br J Radiol, 78 (930), 528-32
    PubMed 15900058
  4. Eikenes L, Tari M, Tufto I, Bruland OS, de Lange Davies C (2005)
    Hyaluronidase induces a transcapillary pressure gradient and improves the distribution and uptake of liposomal doxorubicin (Caelyx) in human osteosarcoma xenografts
    Br J Cancer, 93 (1), 81-8
    PubMed 15942637
  5. Henriksen G, Bruland OS, Larsen RH (2005)
    Preparation and preclinical assessment of folate-conjugated, radiolabelled antibodies
    Anticancer Res, 25 (1A), 9-15
    PubMed 15816513
  6. Nilsson S, Larsen RH, Fosså SD, Balteskard L, Borch KW, Westlin JE, Salberg G, Bruland OS (2005)
    First clinical experience with alpha-emitting radium-223 in the treatment of skeletal metastases
    Clin Cancer Res, 11 (12), 4451-9
    PubMed 15958630
  7. Norum J, Bruland ØS, Spanne O, Bergmo T, Green T, Olsen DR, Olsen JH, Sjåeng EE, Burkow T (2005)
    Telemedicine in radiotherapy: a study exploring remote treatment planning, supervision and economics
    J Telemed Telecare, 11 (5), 245-50
    PubMed 16035967
  8. Onda M, Bruland ØS, Pastan I (2005)
    TP-3 immunotoxins improve antitumor activity in mice with osteosarcoma
    Clin Orthop Relat Res (430), 142-8
    PubMed 15662316

Publications 2004

  1. Bruheim S, Bruland OS, Breistol K, Maelandsmo GM, Fodstad O (2004)
    Human osteosarcoma xenografts and their sensitivity to chemotherapy
    Pathol Oncol Res, 10 (3), 133-41
    PubMed 15448748
  2. Eikenes L, Bruland ØS, Brekken C, Davies Cde L (2004)
    Collagenase increases the transcapillary pressure gradient and improves the uptake and distribution of monoclonal antibodies in human osteosarcoma xenografts
    Cancer Res, 64 (14), 4768-73
    PubMed 15256445
  3. Henriksen G, Bruland OS, Larsen RH (2004)
    Thorium and actinium polyphosphonate compounds as bone-seeking alpha particle-emitting agents
    Anticancer Res, 24 (1), 101-5
    PubMed 15015582
  4. Henriksen G, Schoultz BW, Michaelsen TE, Bruland ØS, Larsen RH (2004)
    Sterically stabilized liposomes as a carrier for alpha-emitting radium and actinium radionuclides
    Nucl Med Biol, 31 (4), 441-9
    PubMed 15093814

Publications 2003

  1. Dale E, Hellebust TP, Bruland ØS, Olsen DR (2003)
    Comparative analyses of the dynamic properties of the rectum studied by cryo-sections of human cadavers and pelvic CT scans of patients
    Br J Radiol, 76 (902), 104-8
    PubMed 12642278
  2. Henriksen G, Fisher DR, Roeske JC, Bruland ØS, Larsen RH (2003)
    Targeting of osseous sites with alpha-emitting 223Ra: comparison with the beta-emitter 89Sr in mice
    J Nucl Med, 44 (2), 252-9
    PubMed 12571218
  3. Olstad OK, Gautvik VT, Reppe S, Rian E, Jemtland R, Ohlsson C, Bruland OS, Gautvik KM (2003)
    Molecular heterogeneity in human osteosarcoma demonstrated by enriched mRNAs isolated by directional tag PCR subtraction cloning
    Anticancer Res, 23 (3B), 2201-16
    PubMed 12894494

Publications 2002

  1. Anderson PM, Wiseman GA, Dispenzieri A, Arndt CA, Hartmann LC, Smithson WA, Mullan BP, Bruland OS (2002)
    High-dose samarium-153 ethylene diamine tetramethylene phosphonate: low toxicity of skeletal irradiation in patients with osteosarcoma and bone metastases
    J Clin Oncol, 20 (1), 189-96
    PubMed 11773169
  2. Aurlien E, Kvinnsland Y, Larsen RH, Bruland ØS (2002)
    Radiation doses to non-Hodgkin's lymphoma cells and normal bone marrow exposed in vitro. Comparison of an alpha-emitting radioimmunoconjugate and external gamma-irradiation
    Int J Radiat Biol, 78 (2), 133-42
    PubMed 11779363
  3. Henriksen G, Breistøl K, Bruland ØS, Fodstad Ø, Larsen RH (2002)
    Significant antitumor effect from bone-seeking, alpha-particle-emitting (223)Ra demonstrated in an experimental skeletal metastases model
    Cancer Res, 62 (11), 3120-5
    PubMed 12036923
  4. Kvinnsland Y, Bruland O, Moe L, Skretting A (2002)
    A method for measurement of the uptake patterns of two beta-emitting radionuclides in the same tissue section with a digital silicon detector: application to a study of 89SrCl2 and 153Sm-EDTMP in a dog with spontaneous osteosarcoma
    Eur J Nucl Med Mol Imaging, 29 (2), 191-7
    PubMed 11926381
  5. Ree AH, Bratland A, Kroes RA, Aasheim HC, Flørenes VA, Moskal JR, Fodstad O, Bruland OS, Maelandsmo GM (2002)
    Clinical and cell line specific expression profiles of a human gene identified in experimental central nervous system metastases
    Anticancer Res, 22 (4), 1949-57
    PubMed 12174869
  6. Saeter G, Hall KS, Bruland ØS, Solheim ØP, Høie J, Follerås G, Helgerud P, Stenwig AE, Bjerkehagen B, Talle K, Taksdal I, Winderen M (2002)
    [Bone and soft tissue sarcomas treated at the Norwegian Radium Hospital 1980-99]
    Tidsskr Nor Laegeforen, 122 (21), 2089-94
    PubMed 12555642

Publications 2001

  1. Hassfjell S, Ingebrigtsen K, Bruland ØS (2001)
    Synthesis, purification and biodistribution of (205)Bi-DOTMP, visualizing bone deposition patterns with autoradiography
    Nucl Med Biol, 28 (4), 425-33
    PubMed 11395316
  2. Kvinnsland Y, Skretting A, Bruland OS (2001)
    Radionuclide therapy with bone-seeking compounds: Monte Carlo calculations of dose-volume histograms for bone marrow in trabecular bone
    Phys Med Biol, 46 (4), 1149-61
    PubMed 11324957
  3. Onda M, Olafsen T, Tsutsumi Y, Bruland OS, Pastan I (2001)
    Cytotoxicity of antiosteosarcoma recombinant immunotoxins composed of TP-3 Fv fragments and a truncated Pseudomonas exotoxin A
    J Immunother, 24 (2), 144-50
    PubMed 11265772

Publications 2000

  1. Aurlien E, Larsen RH, Akabani G, Olsen DR, Zalutsky MR, Bruland OS (2000)
    Exposure of human osteosarcoma and bone marrow cells to tumour-targeted alpha-particles and gamma-irradiation: analysis of cell survival and microdosimetry
    Int J Radiat Biol, 76 (8), 1129-41
    PubMed 10947126
  2. Aurlien E, Larsen RH, Kvalheim G, Bruland OS (2000)
    Demonstration of highly specific toxicity of the alpha-emitting radioimmunoconjugate(211)At-rituximab against non-Hodgkin's lymphoma cells
    Br J Cancer, 83 (10), 1375-9
    PubMed 11044364
  3. Braendengen M, Bruland OS, Olsen DR (2000)
    [Radiotherapy of skeletal metastases]
    Tidsskr Nor Laegeforen, 120 (16), 1870-4
    PubMed 10925615
  4. Brekken C, Bruland ØS, de Lange Davies C (2000)
    Interstitial fluid pressure in human osteosarcoma xenografts: significance of implantation site and the response to intratumoral injection of hyaluronidase
    Anticancer Res, 20 (5B), 3503-12
    PubMed 11131654
  5. Brekken C, Hjelstuen MH, Bruland ØS, de Lange Davies C (2000)
    Hyaluronidase-induced periodic modulation of the interstitial fluid pressure increases selective antibody uptake in human osteosarcoma xenografts
    Anticancer Res, 20 (5B), 3513-9
    PubMed 11131655
  6. Pihl A, Bruland OS (2000)
    Oral presentations in science and medicine. An art in decline?
    Anticancer Res, 20 (5A), 2795-9
    PubMed 11062686

Publications 1999

  1. Jemtland R, Rian E, Olstad OK, Haug E, Bruland OS, Bucht E, Gautvik KM (1999)
    Two human osteoblast-like osteosarcoma cell lines show distinct expression and differential regulation of parathyroid hormone-related protein
    J Bone Miner Res, 14 (6), 904-14
    PubMed 10352098
  2. Larsen RH, Murud KM, Akabani G, Hoff P, Bruland OS, Zalutsky MR (1999)
    211At- and 131I-labeled bisphosphonates with high in vivo stability and bone accumulation
    J Nucl Med, 40 (7), 1197-203
    PubMed 10405142
  3. Murud KM, Larsen RH, Bruland OS, Hoff P (1999)
    Influence of pretreatment with 3-amino-1-hydroxypropylidene-1,1-bisphosphonate (APB) on organ uptake of 211At and 125I-labeled amidobisphosphonates in mice
    Nucl Med Biol, 26 (7), 791-4
    PubMed 10628558
  4. Olafsen T, Munthe Lund CK, Bruland OS, Sandlie I, Michaelsen TE (1999)
    Complement-mediated lysis of cultured osteosarcoma cell lines using chimeric mouse/human TP-1 IgG1 and IgG3 antibodies
    Cancer Immunol Immunother, 48 (7), 411-8
    PubMed 10501855
  5. Ree AH, Tvermyr M, Engebraaten O, Rooman M, Røsok O, Hovig E, Meza-Zepeda LA, Bruland OS, Fodstad O (1999)
    Expression of a novel factor in human breast cancer cells with metastatic potential
    Cancer Res, 59 (18), 4675-80
    PubMed 10493524
  6. Tanum G, Bruland OS, Hjelle D, Reitan JB (1999)
    [Patient treatment in radiation accidents]
    Tidsskr Nor Laegeforen, 119 (10), 1446-50
    PubMed 10354753
  7. Aas M, Moe L, Gamlem H, Skretting A, Ottesen N, Bruland OS (1999)
    Internal radionuclide therapy of primary osteosarcoma in dogs, using 153Sm-ethylene-diamino-tetramethylene-phosphonate (EDTMP)
    Clin Cancer Res, 5 (10 Suppl), 3148s-3152s
    PubMed 10541356

Publications 1998

  1. Hassfjell SP, Skretting A, Bruland OS, Hoff P (1998)
    Predicting detectability in radioguided surgery: a study based on physical characterization of the probe and on tissue uptake ratios of 125I-, 153Sm- and 165Er-labelled radiopharmaceuticals
    Nucl Med Commun, 19 (3), 207-17
    PubMed 9625495
  2. Larsen RH, Bruland OS (1998)
    Intratumour injection of immunoglobulins labelled with the alpha-particle emitter 211At: analyses of tumour retention, microdistribution and growth delay
    Br J Cancer, 77 (7), 1115-22
    PubMed 9569048
  3. Lopes JM, Hannisdal E, Bjerkehagen B, Bruland OS, Danielsen HE, Pettersen EO, Sobrinho-Simões M, Nesland JM (1998)
    Synovial sarcoma. Evaluation of prognosis with emphasis on the study of DNA ploidy and proliferation (PCNA and Ki-67) markers
    Anal Cell Pathol, 16 (1), 45-62
    PubMed 9584899
  4. Olafsen T, Rasmussen IB, Norderhaug L, Bruland OS, Sandlie I (1998)
    IgM secretory tailpiece drives multimerisation of bivalent scFv fragments in eukaryotic cells
    Immunotechnology, 4 (2), 141-53
    PubMed 9853955
  5. Olsen DR, Bruland OS (1998)
    Radiotherapy in Scandinavia
    Acta Oncol, 37 (6), 553-60
    PubMed 9860313

Publications 1997

  1. Bruland OS, Pihl A (1997)
    On the current management of osteosarcoma. A critical evaluation and a proposal for a modified treatment strategy
    Eur J Cancer, 33 (11), 1725-31
    PubMed 9470825
  2. Ekstrøm PO, Giercksky KE, Andersen A, Bruland OS, Slørdal L (1997)
    Intratumoral differences in methotrexate levels within human osteosarcoma xenografts studied by microdialysis
    Life Sci, 61 (19), PL275-80
    PubMed 9364204
  3. Hassfjell SP, Bruland OS, Hoff P (1997)
    212Bi-DOTMP: an alpha particle emitting bone-seeking agent for targeted radiotherapy
    Nucl Med Biol, 24 (3), 231-7
    PubMed 9228657
  4. Lopes JM, Bruland OS, Bjerkehagen B, Silva MC, Holm R, Pettersen EO, Solheim OP, Sobrinho-Simões M, Nesland JM (1997)
    Synovial sarcoma: immunohistochemical expression of P-glycoprotein and glutathione S transferase-pi and clinical drug resistance
    Pathol Res Pract, 193 (1), 21-36
    PubMed 9112270

Publications 1996

  1. Bruland OS, Skretting A, Solheim OP, Aas M (1996)
    Targeted radiotherapy of osteosarcoma using 153 Sm-EDTMP. A new promising approach
    Acta Oncol, 35 (3), 381-4
    PubMed 8679270
  2. Gordeladze JO, Lund HW, Jablonski G, Bruland OS (1996)
    Diverse expression of G-proteins in human sarcoma cell lines with different osteogenic potential: evidence for the involvement of Gi2 in cell proliferation
    J Cell Biochem, 60 (1), 95-106
    PubMed 8825419
  3. Moe L, Boysen M, Aas M, Lønaas L, Gamlem H, Bruland OS (1996)
    Maxillectomy and targeted radionuclide therapy with 153Sm-EDTMP in a recurrent canine osteosarcoma
    J Small Anim Pract, 37 (5), 241-6
    PubMed 8736231
  4. Olafsen T, Bruland OS, Zalutsky MR, Sandlie I (1996)
    Abundant tyrosine residues in the antigen binding site in anti-osteosarcoma monoclonal antibodies TP-1 and TP-3: Application to radiolabeling
    Acta Oncol, 35 (3), 297-301
    PubMed 8679259
  5. Saeter G, Bruland OS, Follerås G, Boysen M, Høie J (1996)
    Extremity and non-extremity high-grade osteosarcoma -- the Norwegian Radium Hospital experience during the modern chemotherapy era
    Acta Oncol, 35 Suppl 8, 129-34
    PubMed 9073059

Publications 1995

  1. Bruland OS (1995)
    Cancer therapy with radiolabeled antibodies. An overview
    Acta Oncol, 34 (8), 1085-94
    PubMed 8608033
  2. Larsen RH, Hoff P, Vergote IB, Bruland OS, Aas M, De Vos L, Nustad K (1995)
    Alpha-particle radiotherapy with 211At-labeled monodisperse polymer particles, 211At-labeled IgG proteins, and free 211At in a murine intraperitoneal tumor model
    Gynecol Oncol, 57 (1), 9-15
    PubMed 7705707
  3. Olafsen T, Bruland OS, Zalutsky MR, Sandlie I (1995)
    Cloning and sequencing of V genes from anti-osteosarcoma monoclonal antibodies TP-1 and TP-3: location of lysine residues and implications for radiolabeling
    Nucl Med Biol, 22 (6), 765-71
    PubMed 8535337

Publications 1994

  1. Bruland OS, Fodstad O, Aas M, Solheim OP, Høie J, Skretting A, Winderen M, Michaelsen T, Pihl A (1994)
    Immunoscintigraphy of bone sarcomas--results in 5 patients
    Eur J Cancer, 30A (10), 1484-9
    PubMed 7833107
  2. Larsen RH, Bruland OS, Hoff P, Alstad J, Lindmo T, Rofstad EK (1994)
    Inactivation of human osteosarcoma cells in vitro by 211At-TP-3 monoclonal antibody: comparison with astatine-211-labeled bovine serum albumin, free astatine-211 and external-beam X rays
    Radiat Res, 139 (2), 178-84
    PubMed 8052693
  3. Larsen RH, Bruland OS, Hoff P, Alstad J, Rofstad EK (1994)
    Analysis of the therapeutic gain in the treatment of human osteosarcoma microcolonies in vitro with 211At-labelled monoclonal antibody
    Br J Cancer, 69 (6), 1000-5
    PubMed 8198960
  4. Page RL, Garg PK, Garg S, Archer GE, Bruland OS, Zalutsky MR (1994)
    PET imaging of osteosarcoma in dogs using a fluorine-18-labeled monoclonal antibody Fab fragment
    J Nucl Med, 35 (9), 1506-13
    PubMed 8071702

Publications 1993

  1. Andreassen A, Oyjord T, Hovig E, Holm R, Flørenes VA, Nesland JM, Myklebost O, Høie J, Bruland OS, Børresen AL (1993)
    p53 abnormalities in different subtypes of human sarcomas
    Cancer Res, 53 (3), 468-71
    PubMed 8425179

Publications 1992

  1. Flørenes VA, Aamdal S, Myklebost O, Maelandsmo GM, Bruland OS, Fodstad O (1992)
    Levels of nm23 messenger RNA in metastatic malignant melanomas: inverse correlation to disease progression
    Cancer Res, 52 (21), 6088-91
    PubMed 1356624
  2. Haines DM, Bruland OS, Matte G, Wilkinson AA, Meric SM, Fowler JD (1992)
    Immunoscintigraphic detection of primary and metastatic spontaneous canine osteosarcoma with F(ab')2 fragments of osteosarcoma-associated monoclonal antibody TP-1
    Anticancer Res, 12 (6B), 2151-7
    PubMed 1295462

Publications 1990

  1. Fjeld JG, Bruland OS, Benestad HB, Schjerven L, Stigbrand T, Nustad K (1990)
    Radioimmunotargeting of human tumour cells in immunocompetent animals
    Br J Cancer, 62 (4), 573-8
    PubMed 2223574

Publications 1989

  1. Haines DM, Bruland OS (1989)
    Immunohistochemical detection of osteosarcoma-associated antigen in canine osteosarcoma
    Anticancer Res, 9 (4), 903-7
    PubMed 2684000

Publications 1988

  1. Bruland OS, Fodstad O, Stenwig AE, Pihl A (1988)
    Expression and characteristics of a novel human osteosarcoma-associated cell surface antigen
    Cancer Res, 48 (18), 5302-9
    PubMed 2457439

 
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